HU-211 is Uncontrolled in the United States. Although, it may fall under the analog act since it is it is categorized as a THC substance and is similar to those THC substances that occur naturally in marijuana.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: NMDA receptor blocker



HU-211 is structurally similar to Δ9-tetrahydrocannabinol (Δ9-THC), the main active ingredient of marijuana. It was synthesized around 1988. It is used in scientific research as a pharmacological tool to study the brain, and is being explored for several therapeutic uses. It was recently purported to be found in Spice. HU-211 is not a controlled substance in the U.S, although based on the structural analysis of HU-211, it is categorized as a THC substance and is similar to those THC substances that occur naturally in marijuana.

Behavioral pharmacology studies show that HU-211 does not have Δ9-THC-like activity in animals. Phase I, phase II, and phase III clinical studies of HU-211’s safety and efficacy in traumatic brain injury patients did not observe any psychotropic effects in humans.


Side Effects and Adverse Reactions:

HU-211 is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.


HU-211 and Drug Tests:

HU-211 is a synthetic cannabinoid that currently cannot be detected with drug tests. This is because of how drug tests work. The basic concept is that your body attempts to break down any drugs you ingest. Metabolites are formed as part of this process; testing looks for the specific types of metabolites that could only occur as a result of drug taking. There is currently (as of Nov, 2009) no test that tests for the metabolites of synthetic cannabinoids. Rumor has it that scientists are developing a drug test that tests for them, although, the development and implementation process could take years.



HU-211 in Drugs and Chemicals of Concern (DEA Website)



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