Bufotenine 5-OH-DMT


Bufotenine (5-OH-DMT) is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute (sell, trade or give) without a DEA license. Not available by prescription.

Addictive Potential: None

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Increases the Neurotransmitter Serotonin


The Name Bufotenine, also spelled Bufotenin, originates from the psychoactive toad Bufo Alvarius, which secretes 5-MeO-DMT and Bufotenine from their glands. It is very similar to the chemical structure of serotonin.

Bufotenine is basically inactive even though it is classified as a Schedule I hallucinogen. The United States government deemed Bufotenine as a "dangerous drug" with results from one study of 14 schizophrenic patients at a state mental hospital and two convicts in a state prison. They injected the convicts over the course of three minutes with a solution of Bufotenine as the salt. In this single observation they observed a release of serotonin in the blood. This was all the data they needed to make it illegal.



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