LSD Lysergic Acid Diethylamide


LSD is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute (sell, trade or give) without a DEA license. more...

Addictive Potential: None

Emergency Room Visits Yearly: 656 in 2003 more...

Mandatory Minimum Sentence: 5 years for 1-9 grams mixture

Mechanism of Action: partial agonist of the serotonin receptors primarly at the 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A, 5-HT5B, and 5-HT6


Lysergic acid diethylamide is also commonly called LSD, LSD-25, or acid. LSD is an entheogen, or hallucinogen that some people use during spiritual practices.

It is synthesized from lysergic acid derived from ergot, a grain fungus that typically grows on rye. The short form LSD comes from its early codename LSD-25, which is an abbreviation for the German "Lysergsäure-diethylamid" followed by a sequential number.

LSD is sensitive to oxygen, ultraviolet light, and chlorine, especially in solution, though its potency may last years if it is stored away from light and moisture at low temperature. In pure form it is colorless, odorless and mildly bitter. LSD is typically delivered orally, usually on a substrate such as absorbent blotter paper, a sugar cube, or gelatin. In its liquid form, it can be administered by intra muscular or intravenous injection. The threshold dosage level for an effect on humans is of the order of 20 to 30 µg (micrograms). more...

Introduced by Sandoz Laboratories as a drug with various psychiatric uses, LSD quickly became a therapeutic agent that appeared to show great promise. However, the extra-medical use of the drug in Western society in the middle years of the twentieth century led to a political firestorm that resulted in the banning of the substance for medical as well as recreational and spiritual uses. more...


Side Effects and Adverse Reactions:

The effects of LSD depend largely on the amount taken. LSD causes dilated pupils; can raise body temperature and increase heart rate and blood pressure; and can cause profuse sweating, loss of appetite, sleeplessness, dry mouth, and tremors.

Sensations and feelings change much more dramatically than the physical signs. The user may feel several different emotions at once or swing rapidly from one emotion to another. If taken in large enough doses, the drug produces delusions and visual hallucinations. The user’s sense of time and self is altered. Experiences may seem to “cross over” different senses, giving the user the feeling of hearing colors and seeing sounds. These changes can be frightening and can cause panic. Some LSD users experience severe, terrifying thoughts and feelings of despair, fear of losing control, or fear of insanity and death while using LSD.

LSD users can also experience flashbacks, or recurrences of certain aspects of the drug experience. Flashbacks occur suddenly, often without warning, and may occur within a few days or more than a year after LSD use. In some individuals, the flashbacks can persist and cause significant distress or impairment in social or occupational functioning, a condition known as Hallucinogen Persisting Perception Disorder (HPPD). HPPD from LSD effects can be treated through admission to a rehabilitation center or through outpatient psychotherapy.



An LSD Trip into the Timeless Loop

LSD: Lineage of a Sacrament

LSD, Methamphethamine, Heroin, Cocaine - Where Did They Come From?

Telepathy During an MDMA and LSD Trip

>>>More Videos About LSD (you can upload your own and view others)


Trip Reports:

Dancing Between Mortal Terror and Perfect Comfort

More Trip Reports...



Response of Cluster Headache to Psilocybin and LSD

Hallucinogen Persisting Perception Disorder: what do we know after 50 years?

Flashback: Psychiatric Experimentation with LSD in Historical Perspective

LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex

LSD, Meditation and Music

'Hitting Highs at Rock Bottom': LSD Treatment for Alcoholism, 1950-1970



The NeuroSoup Trip Guide - The free e-book version of The Neurosoup Trip Guide is now available online. It contains chapters on Choosing the Right Hallucinogen; Set, Setting, and Preparation for a Trip; Tips for Tripsitters; Aspects of the Entheogenic Experience; Working with Difficult Experiences; Integration; and References and Recommended Reading.


More Info:

Use Statistics

Similar To...

How to Work With Bad Trips

Buy Legal Entheogens